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The Best Restaurants in Florida Keys, According to our Tastemakers

The best restaurants in the Florida Keys deliver on several compelling fronts. Expansive flavor profiles range from Caribbean-influenced and classic Italian to Asian-fusion. The top eateries across this tropical island chain boast ample seaside venues situated in beachfront cottages, historic mansions, and open-air dock-side terraces. What do the most acclaimed chefs in the Keys have in common? A mastery of fresh local fish and seafood that includes Key West pink shrimp, Florida lobster, and yellowtail snapper. But where do the smartest, most experienced eaters go for an amazing meal in the Florida Keys? Welcome to our Tastemaker List. We pulled data covering thousands of area restaurants to find the best of them all according to OpenTable's savviest users. Together, these restaurants offer every element that makes the Florida Keys so special – sunshine, stunning scenery and delicious cuisine, plus everyone's favorite cool beverages, of course. Anyone heading to the Keys or lucky enough to live there should book a table at one or more today.

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The OpenTable Team
17 Restaurants
Updated February 25, 2020
Restaurants:Nine One Five, La Trattoria Oceanside, Bistro 245
Price Range:$$ - $$$
Cuisines:Contemporary American, Italian
Neighborhoods:Key West
A photo of Nine One Five restaurant

Nine One Five

$$$$
Contemporary American
Key West
4.6
3304 reviews
A sophisticated eatery inside a Victorian home on Key West’s famous Duval Street, Nine One Five presents a refined take on new American cuisine with global influences. It’s one of the best restaurants in the Florida Keys for modern fine dining worthy of special occasions. Award-winning chef Brendan Orr makes room on his lengthy dinner menu for shareables and raw-bar items in addition to handmade pastas, salads and substantial mains. The latter might include seared diver scallops with a pancetta and herb risotto, a filet au poivre with a watercress salad, and the soul mama seafood soup packed with the freshest local seafood. Standout shareables include “absurdly addictive” asparagus with garlic, lemon, pine nuts and pancetta, an artisan cheese plate, and grilled octopus with a chickpea ragout.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of La Trattoria Oceanside restaurant

La Trattoria Oceanside

$$$$
Italian
Key West
4.6
1631 reviews
La Trattoria Oceanside opened in 2011, a testament to the enduring popularity of the original La Trattoria in Old Town, which dates to 1983. Just like its sister restaurant, the Oceanside eatery offers remarkable Italian cuisine with a focus on local fish and seafood. The newer venue stands out, however, with its waterfront setting and a light-filled dining room with walls of windows to emphasize the unmatched views. There are few finer spots in the Keys to enjoy such exemplary dishes as sautéed local hogfish with artichoke and spinach, and linguine fra diavolo with shrimp, mussels and calamari. Don’t miss one of La Trattoria’s 25-plus martinis.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Bistro 245 restaurant

Bistro 245

$$$$
Contemporary American
Key West
4.4
1318 reviews
One of the best restaurants in the Florida Keys for upscale fine dining on the waterfront is Bistro 245. The restaurant sits adjacent to the harbor inside Key West’s Margaritaville Resort, where dinnertime visitors enjoy stunning sunset views. The bistro also offer breakfast, lunch and on Sundays a champagne brunch. Expect plenty of local seafood with nods to the tropics, such as the Caribbean seafood salad in a ginger-mango dressing and truffle-crusted grouper with lobster hash and a tomato lime butter. Other highlights include a surf and turf of broiled Florida lobster and filet mignon, the island gazpacho soup and the ahi tuna tacos with a seaweed salad.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Pierre's Restaurant & Lounge restaurant

Pierre's Restaurant & Lounge

$$$$
Contemporary French / American
Islamorada
4.7
974 reviews
An antique-filled two-story plantation on the waterfront of Islamadora houses one of the best restaurants in the Florida Keys – Pierre’s Restaurant and Lounge. Dinner at Pierre’s is an elegant experience augmented by ocean breezes and a stunning sunset. Chef Ishmael Toro’s signature French-fusion cuisine is notable for its artistic presentation as well as globally inspired flavors. Exemplary dishes include local stone crab claws with a house-made mustard sauce, lionfish tiradito and a Florida lobster curry with forbidden black rice served in a coconut shell. The menu also presents some outstanding non-seafood items, among them a grilled rack of lamb, a sweet and sour vegetable stir fry and grilled Delmonico steak au poivre.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Azur restaurant

Azur

$$$$
Mediterranean
Key West
4.8
2118 reviews
Mediterranean-inspired cuisine showcasing top-quality local ingredients is the signature of Azur in the heart of Old Town Key West. The restaurant presents brunch and dinner in its romantic, sunshine-filled space that also features a terrace. A notable specialty is gnocchi, offered in four preparations on the dinner menu. Also note the “almost entrees” section featuring chorizo-braised oxtail with red quinoa and a pan-roasted chicken with pancetta, haricots verts and chilled Dijon potatoes. The key lime pie French toast that stars on Azur’s brunch menu is a local favorite.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Cafe Marquesa restaurant

Cafe Marquesa

$$$$
Contemporary American
Key West
4.8
2181 reviews
Café Marquesa sits inside the Marquesa Hotel, an Old Town Key West icon comprising a set of 19th-century conch houses restored to their former glory. Fitting with such an exceptional setting is acclaimed chef Graham Dailey’s sophisticated new American cuisine. Local seafood is a focus, often in southern-inspired dishes like she crab soup and pimento cheese baked oysters. The frequently changing dinner menu might also feature a crispy yellowtail snapper with parmesan grits, crab coleslaw and an English pea puree, and seared duck breast with roasted baby carrots and garlic braised greens. House-made desserts and an excellent wine list are also Café Marquesa highlights.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Antonia's restaurant

Antonia's

$$$$
Italian
Key West
4.7
1599 reviews
As a Key West locals’ favorite for more than 30 years, Antonia’s is undoubtedly one of the best restaurants in the Florida Keys. Its home-style, from-scratch Italian cuisine, offered for lunch, dinner and brunch, brings together old-school comfort-food classics like lasagna and veal scallopini with creations showcasing local fish and seafood. Among those are a pan-roasted local grouper with toasted gnocchi, pine nuts, mushrooms and a key lime scallion butter. The zuppa di pesce packs Key West pink shrimp, baby scallops, littleneck clams, squid, mussels and lobster into a fragrant and spicy tomato broth. Antonia’s also offers a Wine Spectator Award of Excellence-winning wine list.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Little Pearl restaurant

Little Pearl

$$$$
Seafood
Key West
4.8
2001 reviews
With chic nautical décor to complement its seafood-centric menu, Little Pearl is a delightful little restaurant in Key West. It’s of the best restaurants in the Florida Keys to dine on innovative and modern cuisine with diverse global flavors. Chef John Inelsby brings together influences from southern to pan-Asian cuisine, all showcasing local ingredients of the highest quality. A signature entrée is the lobster, shrimp and crab pot pie. Bangkok octopus with herbs and mung beans, sake-steams clams and a shrimp bruschetta are highlights among the appetizers. Little Pearl’s dinner menu also includes a raw bar section featuring oysters on the half shell, caviar service and both a poke and ceviche du jour.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?


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A photo of Seven Fish restaurant

Seven Fish

$$$$
Seafood
Key West
4.6
2257 reviews
In a striking venue with floor-to-ceiling windows in Key West, Seven Fish offers excellent local seafood dishes, often with exotic tropical flavors. Standout items on the dinner menu include sushi rolls (spicy tuna or sautéed grouper), a Florida-style crab cake with ginger-garlic sauce, and an entrée of sea scallops over mashed potatoes with a pea and spinach puree. There’s also the chef’s selection, a seafood feast for one or two with grilled fish, jumbo sea scallops and shrimp plus sushi rice and vegetables. Unusually for a seafood restaurant, Seven Fish’s signature entrée is a chicken dish – the intriguing banana chicken with caramelized walnuts.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Tavern N' Town - Marriott Key West restaurant

Tavern N' Town - Marriott Key West

$$$$
American
Key West
4.6
1756 reviews
Tavern N’ Town, the signature restaurant of the Marriott Key West hotel, specializes in shareable cuisine. Its dinner menu features tapas, salads, soups, rustic pizzas, entrees from the land and sea, and a dozen different side dishes. Among the tapas are beef tenderloin or black grouper tacos, a jumbo pink shrimp cocktail and crisp fried calamari with lemon aioli and a Creole cocktail sauce. Hearty meat dishes include balsamic-braised bison ribs with bourbon mashed yams, a rack of Colorado lamb and a signature prime rib au jus. Plancha pink shrimp and sea scallops, a lobster, crab and pink shrimp fettuccini and a pistachio-crusted black grouper with charred tomato couscous star on the seafood section of the menu.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Angler & Ale at Hawks Cay restaurant

Angler & Ale at Hawks Cay

$$$$
Caribbean
Duck Key
4.3
574 reviews
Sunny, dockside seating and a cheerful, nautical-themed dining room complement the friendly atmosphere at Angler and Ale, an upscale-casual lunch and dinner spot at Hawks Cay Resort. Local ingredients and Caribbean-leaning flavors feature on its lengthy menus, which naturally showcase an abundance of just-caught fish and seafood. Just a few highlights are Caribbean conch fritters with key lime aioli, jumbo lump crab cakes with a salt-and-vinegar-chip crust, Key West peel-n-eat shrimp by the half- or full-pound, and the local catch of the day blackened or grilled. An array of burgers and sandwiches are tempting options as well.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of DiGiorgio's Cafe Largo restaurant

DiGiorgio's Cafe Largo

$$$$
Italian
Key Largo
4.3
800 reviews
A feature on Food Network’s “Diners, Drive-In and Dives” brought national attention to DiGiorgio’s Café Largo, but locals already regarded the family-run Italian-American eatery one of the best restaurants in the Florida Keys. The popular Key Largo establishment sources seafood from its neighbor, Key Largo Fisheries, and offers the freshest catch of the day in a choice of parmesan-crusted, piccata or roasted garlic preparations. Other great choices include a seafood linguini marinara, wild-caught pink shrimp scampi and comfort-food classics like lasagna and eggplant parmigiana al forno. Personal pizzas are featured as well.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Castaway Waterfront Restaurant & Sushi Bar restaurant

Castaway Waterfront Restaurant & Sushi Bar

$$$$
Seafood
Marathon
4.6
1170 reviews
A Marathon institution, Castaway Waterfront Restaurant and Sushi Bar dates to 1951. From its early days the eatery stuck with a simple, winning concept of offering cold drinks and fresh seafood. In contemporary times those two key offerings remain, joined by 52 beers on tap and a full lineup of sushi. The restaurant also expanded its hours, opening all day, every day for breakfast, lunch, dinner and a four-hour-long happy hour. Castaway’s menus all reveal a something-for-everyone approach. Dozens upon dozens of options range from shrimp cocktail and calamari appetizers to fresh local lobster in four different preparations.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of A&B Lobster House restaurant

A&B Lobster House

$$$$
Seafood
Key West
4.6
3468 reviews
A&B Lobster House, a Key West icon since 1947, is one of the longest-running and certainly one of the best restaurants in the Florida Keys. Its waterfront setting, with views over Key West Bight from a wrap-around porch as well as the main dining room, is unrivaled. Lobster is, of course, a key feature of its dinner menu. Maine and Florida lobsters from two to five pounds are showcased in seven main course options, as well as starters including a Cognac-infused bisque. Don’t overlook prime steaks and slow-roasted prime rib as an alternative to top-notch seafood.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Bagatelle restaurant

Bagatelle

$$$$
Seafood
Key West
4.6
2906 reviews
A 19th-century, two-story house on Duval Street in Key West is home to Bagatelle, an approachable fine-dining restaurant specializing in southern and Caribbean flavors. Its wine list is exceptional. Bagatelle’s signature lobster mac and cheese is a star of the brunch and dinner menus, both of which are offered daily. Other brunch highlights include the crab cake Benedict with key lime hollandaise, and the banana Foster French toast with a dark rum sauce and whipped cream. Dinner focuses on seafood dishes, among them a chilled Mediterranean octopus appetizer, whole fried lobster snapper and a lightly blackened swordfish with a roasted corn and black bean risotto.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

A photo of Southernmost Beach Cafe restaurant

Southernmost Beach Cafe

$$$$
Caribbean
Key West
3.7
1082 reviews
With a “boat to table” concept, ocean views and chef Matt Slattery’s tempting cuisine, Southernmost Beach Café draws an appreciative crowd of locals and tourists alike. Seafood-centric signatures reveal Asian and Caribbean influences, but most showcase ingredients sourced locally. A notable entree is the drunken scallops with lobster mash, while the fresh catch of the day in one of five distinct preparations is a fail-safe choice. Meanwhile, small plates including Bahamian conch fritters, lobster aranchini, house-smoked pork belly and grouper cheek tacos tempt diners to mix and match an array of items to share.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?


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A photo of Latitudes Key West, FL on Sunset Key restaurant

Latitudes Key West, FL on Sunset Key

$$$$
Contemporary American
Key West
4.8
11797 reviews
Among many accolades, Food & Wine named Latitudes on Sunset Key the most romantic restaurant in Florida. Rest assured it’s just as impressive a venue for any non-romantic occasion as well. The restaurant’s setting right on the Gulf of Mexico within the Sunset Key Cottages resort is unmatched, and during sunset truly remarkable. So is the cuisine, which takes a sophisticated approach to showcasing local seafood. The menu stars modernized classics like carpaccio spiced ahi tuna with caper meringue, a Tuscan kale salad with pistachios and shaved fennel, and seared sea scallops with turmeric, a beet-citrus sauce and mango chayote salad.

At the moment, there's no online availability within 2.5 hours of your request. Do you have another time in mind?

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