42 Best Southern American Restaurants In Serra Mesa

42 restaurants available nearby

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A photo of Louisiana Purchase SD restaurant

1. Louisiana Purchase SD

4.3

Awesome(1054)

$$$$

• Southern • North Park

Booked 30 times today

Great restaurant! The food was amazing! I had the oysters, mac & cheese and the house biscuits! Everything tasted great. Their playlist was top-tier R&B chill vibes. The whole staff was friendly and welcoming. I sat at the bar, the bartender was so kind and very attentive. The restaurant was clean and I will be back next time I’m in San Diego!

2. Nick's Del Mar

4.7

Exceptional(1951)

$$$$

• Southern • Del Mar

Booked 79 times today

We really enjoy coming to Nick's. For lunch and for dinner, equally enjoyable experiences. Service is always great, they go out of their way to accommodate any wish or need. Our reservation was at 8:15 but we got there at 7, and they sat us right away. Food is high quality, everything cooked to perfection and flavor.

A photo of Lazy Dog Restaurant & Bar - Mission Valley restaurant

3. Lazy Dog Restaurant & Bar - Mission Valley

4.5

Awesome(183)

$$$$

• Southern • Mission Valley

Booked 25 times today

This was a great experience. Our Open Table reservation was perfect here. We walked up to the host/hostess station, stated the reservation and they seated us right away. The server was great and our food was prepared perfectly. The red wine that I had was great. The butter cake dessert was delicious and well prepared. Thanks!

A photo of South of Nick's - Del Mar restaurant

4. South of Nick's - Del Mar

4.7

Exceptional(1170)

$$$$

• Southern • Del Mar

Booked 54 times today

Amazing service, absolutely delicious food. Incredible margaritas!

A photo of Bud's Louisiana Cafe restaurant

5. Bud's Louisiana Cafe

4.7

Exceptional(69)

$$$$

• Southern • Kearny Mesa

Booked 8 times today

Excellent food & service. There are many very good choices on the menu. This time, I had the catfish special, and it was wonderful. Ben, the waiter, was great,

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6. Paradisaea

4.8

Exceptional(961)

$$$$

• Southern • La Jolla

Booked 33 times today

Fantastic food and service. We had the chefs tasting menu and were thoroughly impressed!

7. CUCINA urbana

4.7

Exceptional(7307)

$$$$

• Southern • Banker's Hill

Booked 28 times today

Delicious food. Service was very attentive but not over bearing.

8. Between Us

4.6

Exceptional(22)

$$$$

• Southern • North Park

Booked 23 times today

The food and presentation was consistent and absolutely delicious. Service staff seemed very rushed - bumped into my table or me at least four times. I had to lean over in my seat to avoid getting bumped by the waitress whenever she walked by. Would return to try other food items on the menu nonetheless.

A photo of Birdseye Rooftop Bar and Restaurant restaurant

9. Birdseye Rooftop Bar and Restaurant

4.3

Awesome(40)

$$$$

• Southern • La Jolla

Booked 12 times today

Everyone was so fun and welcoming had such a great time celebrating my birthday

10. Brockton Villa

4.5

Awesome(2971)

$$$$

• Southern • La Jolla

Booked 8 times today

Thank You for the fantastic food and service!! It was wonderful

Best Southern American Restaurants in Serra Mesa

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Top Rated

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Award-winning

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42 restaurants available nearby

1. Louisiana Purchase SD

2. Nick's Del Mar

3. Lazy Dog Restaurant & Bar - Mission Valley

4. South of Nick's - Del Mar

5. Bud's Louisiana Cafe

6. Paradisaea

7. CUCINA urbana

8. Between Us

9. Birdseye Rooftop Bar and Restaurant

10. Brockton Villa

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